Nefesh HaChayim, Reb Itzele's Long Annotation

And thus, the Holy One’s (blessed be He) will was to:• Bring [everything] into existence via the three mothers: alef, mem and shin• That vessels should be brought into existence level by level, and• At each level the elements would combine in different ways, and• That via each and every vessel according to its qualities, would be recognized via different qualities whose desire was to be drawn upwards, and• Also to influence downwards to the vessel below it, so that even in the vessel at the lowest possible level would be brought into existence the original intention: to ascend to the highest.