Nefesh HaChayim, Reb Itzele's Long Annotation

And it, the mem of the tzellem, is the four supernal elements. Each element is split into ten aspects (as is known). And the lamed of the tzellem surrounds the three “mothers” that cause their effects via their combinations in the brain. And the tzaddik is the internal brains based on the three “mothers” that enter into the body in the three vessels: brain, heart and liver. And this is what is explained in the Etz Chayyim, that the tzaddik flows into the entire body of Z’eir Ahnpin477Z’eir Ahnpin is the pahrtzoof corresponding to the vav of the Tetragrammaton, the Holy One (blessed be He), and the world of Y’tzeera. in nine parts, and the lamed into half of Z’eir Ahnpin.